Appeal No. 1998-1488
Application No. 08/100,907
Claim 20 is illustrative of the subject matter on appeal and reads as follows:
20. A process for preparing an enantiomeric form of the compound having the
formula:
or a pharmaceutically acceptable acid addition salt thereof,
wherein said process comprises the steps of:
(a) reacting a racemic mixture of said compound with chiral 4, 5-dihydro-1H-2-
benzopyran-2-carboxylic acid or the acid chloride thereof, to form a mixture of
diastereomeric esters;
(b) physically separating said mixture of diastereomeric esters by chromatography;
and
(c) converting said separated diastereomeric salts or esters into the corresponding
enantiomeric forms of said compound by hydrolysis in an acidic or basic aqueous
medium.
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