Ex Parte BIGGE et al - Page 8


              Appeal No. 1998-2089                                                                                     
              Application 08/443,507                                                                                   
              treatment for a variety of neurodegenerative disorders.  These disorders include, inter                  
              alia, lathyrism, Alzheimer’s disease, Huntington’s disease, schizophrenia, Parkinson’s                   
              disease, epilepsy, drug addiction, and a number of cerebrovascular disorders.  We                        
              agree with the examiner that, at the time applicants’ invention was made, it was                         
              recognized by persons having ordinary skill in the art that these disorders were difficult               
              to treat, i.e., resistant to effective pharmaceutical treatment.                                         
                     All in all, we believe that the examiner appropriately assessed the state of the                  
              prior art; the four assays described in applicants’ specification; the breadth of claim 1;               
              the unpredictability of the art; and the nature of the invention, in determining that                    
              applicants’ specification does not teach those skilled in the art how to use the full scope              
              of the claimed invention without undue experimentation.                                                  
                     The examiner’s decision is affirmed.                                                              
                     No time period for taking any subsequent action in connection with this appeal                    
              may be extended under 37 CFR § 1.136(a).                                                                 

                                                     AFFIRMED                                                          



                                                                             )                                         
                                   Sherman D. Winters                       )                                         
                                   Administrative Patent Judge               )                                         
                                                                             )                                         
                                                                             )                                         
                                                                             ) BOARD OF PATENT                         
                                   William F. Smith                         )                                         
                                   Administrative Patent Judge               )   APPEALS AND                           
                                                                             )                                         
                                                                             ) INTERFERENCES                           
                                                                             )                                         
                                   Eric Grimes                              )                                         
                                   Administrative Patent Judge               )                                         

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