Ex parte TERASAWA et al. - Page 5



                 Appeal No. 1998-2587                                                                                     
                 Application No. 08/451,993                                                                               

                 USPQ2d 1618, 1623 (Fed. Cir. 1996) (quoting Ex parte Jackson, 217 USPQ 804,                              
                 807 (Bd. App. 1982)).  See also In re Vaeck, 947 F.2d 488, 495,                                          
                 20 USPQ2d 1438, 1444 (Fed. Cir. 1991) (“That some experimentation may be                                 
                 required is not fatal; the issue is whether the amount of experimentation required                       
                 is ‘undue.’” (emphasis in original); In re Angstadt, 537 F.2d 498, 504, 190 USPQ                         
                 214, 219 (CCPA 1976) (“The key word is ‘undue,’ not ‘experimentation.’”).                                
                         The fact that a claim encompasses inoperative embodiments does not                               
                 necessarily make the claim non-enabled.  See Atlas Powder Co. v. E.I. Du Pont                            
                 De Nemours & Co., 750 F.2d 1569, 1576, 224 USPQ 409, 414 (Fed. Cir. 1984).                               
                 Of course, “if the number of inoperative combinations becomes significant, and in                        
                 effect forces one of ordinary skill in the art to experiment unduly in order to                          
                 practice the claimed invention, the claims might indeed be [non-enabled].”  Id.                          
                 The potential difficulties pointed out by the examiner are not sufficient to show                        
                 that the number, if any, of inoperative embodiments encompassed by the claims                            
                 is so large that undue experimentation would be required practice the claimed                            
                 invention.                                                                                               
                         The examiner also seems not to have fully considered all of the Wands                            
                 factors, including the state of the art, the level of skill in the art, and the guidance                 
                 provided by the specification.  See In re Wands, 858 F.2d 731, 737, 8 USPQ2d                             
                 1400, 1404 (Fed. Cir. 1988).  Organic chemistry is a well-established field and                          
                 practiced by researchers with a high degree of skill.  Surely those skilled in the                       
                 art would be aware that certain salts would be likely to be toxic or water-                              


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