Ex parte FOLEY et al. - Page 8



                 Appeal No. 1999-0031                                                                                
                 Application No. 08/168,438                                                                          

                 as required by the claims.  The examiner relies on either of Sugiyama or                            
                 Hodgson to remedy this deficiency.  The examiner reasons as follows:                                
                        Sugiyama . . . teaches in the claims a method for removing soluble                           
                        poisonous substances from blood by bringing the blood into contact                           
                        with an absorbent which in claim 4 is activated carbon.  In column 2                         
                        lines 40-48, the adsorbents may be porous resins, porous alumina,                            
                        porous glass or ion exchange resins, selected depending upon the                             
                        substances which are to be removed from blood by absorption.                                 
                        Hodgson . . . teaches a column for purifying blood, in column 2                              
                        lines 35-42, the column may be filled with granules having activated                         
                        carbon or polystyrene granules.  In column 2 lines 55-60, other                              
                        polymers are shown.  In column 4 line 6, any known particulate                               
                        absorbent may be used.                                                                       
                        It would have been obvious to one of ordinary skill in the art at the                        
                        time the invention was made to employ the macroporous polymeric                              
                        beads of either Sugiyama or Hodgson in the method of Heinmets to                             
                        remove selected substances from blood because Sugiyama and                                   
                        Hodgson show such porous polymers are compatible with blood                                  
                        and effectively remove selected substances.                                                  
                 Examiner’s Answer, pages 6-7.                                                                       
                        “The PTO has the burden under section 103 to establish a prima facie                         
                 case of obviousness.  It can satisfy this burden only by showing some objective                     
                 teaching in the prior art or that knowledge generally available to one of ordinary                  
                 skill in the art would lead that individua l to combine the relevant teachings of the               
                 references.”  In re Fine, 837 F.2d 1071, 1074, 5 USPQ2d 1596, 1598 (Fed. Cir.                       
                 1988) (citations omitted).  “The consistent criterion for determination of                          
                 obviousness is whether the prior art would have suggested to  one of ordinary                       
                 skill in the art that this process should be carried out and would have a                           
                 reasonable likelihood of success, viewed in the light of the prior art.  Both the                   


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