Appeal No. 1999-0757 Application No. 08/699,083 aperture in the distal end of its distal end region or an aperture which is circumscribed and defined, at least in part, by a radiused tip. Independent claim 41 now recites a cannula insertion member comprising, inter alia, a tube having a distal end region terminating in an aperture and including a blunt radiused tip and a tapered surface. Garrett’s cannula does not have a distal end region with blunt radiused tip or a tapered surface. Buehler’s cannula includes a distal end region having a blunt radiused tip and a tapered surface, but the distal end region does not terminate in an aperture. Independent claim 42 now recites a cannula and injection site in combination comprising, inter alia, a blunt cannula having a tube with a distal end region having a tapered surface and defining an aperture at an extreme distal end thereof. Garrett’s cannula does not have a distal end region with a tapered surface. Buehler’s cannula has a distal end region with a tapered surface, but no aperture at the extreme distal end thereof. The examiner has not cogently explained, nor is it apparent, how or why the combined teachings of Garrett and Buehler would have suggested the selective mix of the various prior art features necessary to arrive at the structure now specified by claims 17, 32, 36, 41 and 42. We are therefore constrained to 7Page: Previous 1 2 3 4 5 6 7 8 9 10 11 NextLast modified: November 3, 2007