Ex Parte JUNE - Page 3




              Appeal No. 1999-1245                                                                                     
              Application No. 08/245,282                                                                               


              Creemer et al (Creemer)                  5,480,906                   Jan. 2, 1996                        
                                                                                   (Filed July 1, 1994)                
              Weisinger et al (Weisinger), “Antiinflammatory Activity of the New Mould Metabolite 11-                  
              Desacetoxy-Wortmannin and of Some of its Derivatives,” Experientia, Vol. 30, pp. 135-                    
              136 (1974)                                                                                               

              Grounds of Rejection                                                                                     
                     Claims 46-60, 85 and 86 stand rejected under 35 U.S.C. § 112, first paragraph                     
              as unpatentable for lack of enablement as to how to make and use the claimed                             
              invention.                                                                                               
                     Claims 46-48, 50-60, 85 and 86 stand rejected under 35 U.S.C. § 103 as                            
              unpatentable for obviousness over Ward 1993 in view of Vandenberghe and Ward                             
              1992.                                                                                                    
                     Claim 49 stand rejected under 35 U.S.C. § 103 as unpatentable for obviousness                     
              over Ward 1993 in view of Vandenberghe, Ward 1992 and Okada.   We reverse each                           
              of the pending rejections.                                                                               


                                                 DISCUSSION                                                            
                     In reaching our decision in this appeal, we have given careful consideration to                   
              the appellant’s specification and claims, to the applied prior art references, and to the                
              respective positions articulated by the appellant and the examiner.                                      



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