Appeal No. 1999-1396 Application No. 08/524,668 this methodology is especially important in cases where the very ease with which the invention can be understood may prompt one “to fall victim to the insidious effect of a hindsight syndrome wherein that which only the invention taught is used against its teacher.” [] Most if not all inventions arise from a combination of old elements. [] Thus, every element of a claimed invention may often be found in the prior art. [] However, identification in the prior art of each individual part claimed is insufficient to defeat patentability of the whole claimed invention. [] Rather, to establish obviousness based on a combination of the elements disclosed in the prior art, there must be some motivation, suggestion or teaching of the desirability of making the specific combination that was made by the applicant. [citations omitted] In other words, “there still must be evidence that ‘a skilled artisan, . . . with no knowledge of the claimed invention, would select the elements from the cited prior art references for combination in the manner claimed.’” Ecolochem Inc. v. Southern California Edison, 227 F.3d 1361, 1375, 56 USPQ2d 1065, 1075-76 (Fed. Cir. 2000). At best, the statement of the rejection establishes that individual parts of the claimed invention were known in the prior art, i.e., E. acervulina was known to be immunogenic, and a protocol for making chicken monoclonal antibodies was known. It may well be, as asserted by the examiner, that a person skilled in the art would have expected a chicken monoclonal antibody raised against the polypeptides on Murray’s Western blot to be “specific to a[n] immunodominant antigen.” Nevertheless, the examiner has not pointed to any evidence of a suggestion to make a chicken antibody specific for Eimeria acervulina in the first place, let alone one specific for an antigen “located on the conoid of the anterior tip of Eimeria acervulina sporozoites,” as required by the claims. 5Page: Previous 1 2 3 4 5 6 7 NextLast modified: November 3, 2007