Ex parte JEM - Page 1




              The opinion in support of the decision being entered today was not written for publication                   
                                      and is not binding precedent of the Board.                                           
                                                                                      Paper No. 18                         

                               UNITED STATES PATENT AND TRADEMARK OFFICE                                                   
                                                     ____________                                                          
                                    BEFORE THE BOARD OF PATENT APPEALS                                                     
                                                AND INTERFERENCES                                                          
                                                     ____________                                                          
                                              Ex parte KWAN-MIN J. JEM                                                     
                                                     ____________                                                          
                                                 Appeal No. 1999-1425                                                      
                                              Application No. 08/393,321                                                   
                                                     ____________                                                          
                                                       ON BRIEF                                                            
                                                     ____________                                                          
              Before ROBINSON, SCHEINER, and ADAMS, Administrative Patent Judges.                                          
              ROBINSON, Administrative Patent Judge.                                                                       

                                                DECISION ON APPEAL                                                         

                     This is a decision on the appeal under 35 U.S.C. § 134 from the examiner's final                      
              rejection of claims 1 - 26, which are all of the claims pending in the application.                          
                     Claims 1 and 10 are illustrative of the subject matter on appeal and read as follows:                 
                     1.     A mechanical method for disruption of plasmid-containing bacterial cells and                   
              release of intact plasmid DNA, comprising the steps of:                                                      
                     a) passing liquid suspension of plasmid-containing bacterial cells through an                         
              impinging-jet homogenizer with a single interaction chamber at an operating pressure of                      
              about 750 to 4,000 psi, whereby the bacterial cells are disrupted and intact plasmid DNA                     
              is released, producing a liquid that contains intact plasmid DNA and disrupted bacterial                     
              cell debris; and                                                                                             







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