3 4
R and R are independently selected from the
group consisting of:
(a) hydrogen,
(b) CF3,
(c) CN,
(d) C alkyl,
1-6
1 1 2 5 6
(e) Q wherein Q is Q , CO H, C(R )(R )OH,
2
(f) -O-Q2,
(g) -S-Q , and2
(h) optionally substituted
(1) -C alkyl-Q ,1-5 1
(2) -O-C alkyl-Q ,1-5 1
(3) -S-C alkyl-Q ,1-5 1
(4) -C alkyl-O-C alkyl-Q , 1
1-3 1-3
(5) -C alkyl-S-C alkyl-Q , 1
1-3 1-3
(6) -C alkyl-O-Q ,1-5 2
(7) -C alkyl-S-Q ,1-5 2
wherein the substituent resides on the alkyl
chain and the substituent is C alkyl, and
1-3
Q is Q , CO H, C(R )(R )OH1 2 2 5 6
Q is CO -C alkyl, tetrazolyl-5-yl, or2 2 1-4
C(R )(R )O-C5 6 1-4alkyl;
5 6 7
R , R and R are each independently selected
from the group consisting of
(a) hydrogen,
(b) C alkyl
1-6
5 6
or R and R together with the carbon to which
they are attached form a saturated monocyclic carbon
ring of 3, 4, 5, 6, or 7.
8
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Last modified: November 3, 2007