The opinion in support of the decision being entered today was not written for publication and is not binding precedent of the Board. Paper No. 19 UNITED STATES PATENT AND TRADEMARK OFFICE __________ BEFORE THE BOARD OF PATENT APPEALS AND INTERFERENCES __________ Ex parte BEI SHAN, R. MARC LEARNED, M. CATHERINE AMARAL, STEVEN L. MCKNIGHT, FABIENNE CHARLES DE LA BROUSSE and JIN-LONG CHEN __________ Appeal No. 2000-04411 Application No. 08/866,942 __________ ON BRIEF __________ Before WILLIAM F. SMITH, SCHEINER and GRIMES, Administrative Patent Judges. SCHEINER, Administrative Patent Judge. DECISION ON APPEAL This is an appeal under 35 U.S.C. § 134 from the final rejection of claims 1-3 and 5-14, the only claims remaining in the application. Claims 1 and 5 are representative of the subject matter on appeal: 1. An isolated genetic knock-in cell, wherein said cell is, or is a progeny of, a genetic knock-in primary cell obtained from a transgenic mouse made by homologous recombination of a targeted native allele with a transgene comprising a sequence encoding a reporter flanked by flanking sequences which effect the homologous recombination of said transgene with said native allele, wherein the expression of said reporter is under the control of native gene expression regulatory sequences of said native allele. 1 Application for patent filed May 31, 1997. According to appellants, this application is a continuation-in-part of application no. 08/707,408, filed September 4, 1996, now U.S. Patent no. 5,780,258.Page: 1 2 3 4 5 6 7 NextLast modified: November 3, 2007