Appeal No. 2000-0893 Page 7
Application No. 08/392,407
Janda et al. (Janda), “Substrate Attenuation: An Approach to Improve Antibody
Catalysis,” Tetrahedron, Vol. 47, No. 14/15, pp. 2503-2506 (1991)
The references relied upon by appellants are:
Schechter et al. (Schechter), “Preferential Formation of Antibodies Specific
toward D-Amino Acid Residues upon Immunization with Poly-DL-peptidyl
Proteins,” Biochemistry, Vol. 6, No. 3, pp. 897-905 (1967)
(Sambrook), Molecular Cloning, a laboratory manual, Volume 3, pp. 18.1-18.8
(E.F. Sambrook et al. eds., 2nd ed., Cold Spring Harbor Laboratory Press 1989)
GROUNDS OF REJECTION
Claims 80-150 stand rejected under 35 U.S.C. § 112, first paragraph, as
being based on an insufficient disclosure to support or enable the scope of the
claimed invention.
Claims 80, 109, and 120 stand rejected under 35 U.S.C. § 112, second
paragraph, as being indefinite in the recitation of the phrase “which corresponds
to activities exhibited by a protease selected from the group consisting of: an
esterase, an amidase, an acetal hydrolase and a glycosidase.”
We affirm the rejection under 35 U.S.C. § 112, second paragraph, and
reverse the rejection under 35 U.S.C. § 112, first paragraph.
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