The opinion in support of the decision being entered today was not written
for publication and is not binding precedent of the Board.
Paper No. 57
UNITED STATES PATENT AND TRADEMARK OFFICE
__________
BEFORE THE BOARD OF PATENT APPEALS
AND INTERFERENCES
__________
Ex parte NICHOLAS S. BODOR
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Appeal No. 2000-2156
Application No. 08/431,727
__________
HEARD: March 7, 2002
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Before WINTERS, SCHEINER, and MILLS, Administrative Patent Judges.
WINTERS, Administrative Patent Judge.
DECISION ON APPEAL
This appeal was taken from the examiner’s decision rejecting claims 110 through
115, 123, and 124, which are all of the claims remaining in the application.
Representative Claim
Claim 123, which is illustrative of the subject matter on appeal, reads as follows:
123. A method for the design of a soft drug entity, the in vivo metabolic
disposition of which proceeds in predictable manner into an inactive metabolite moiety
and nontoxic moieties thereof after eliciting its desired therapeutic response, comprising
(a) identifying a nontoxic, therapeutically inactive candidate metabolite of a given drug
entity known to elicit a particular therapeutic response, and (b) structurally converting
such therapeutically inactive metabolite into an activated, structurally-related drug
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