Ex Parte NORTHRUP - Page 2


              Appeal No. 2001-0103                                                                                     
              Application 08/763,465                                                                                   
                     1.  In a microfabricated chemical reactor, the improvement comprising:                            
                     a sleeve reaction chamber constructed of silicon-based or non-silicon based                       
              materials;                                                                                               
                     said sleeve reaction chamber including a slot therein for insertion of reaction                   
              fluid.                                                                                                   
                     26. The improvement of Claim 1, wherein said sleeve reaction chamber is                           
              constructed and is adapted to be inserted into an instrument constructed to contain an                   
              array of such reaction chambers.                                                                         
                     27.  The improvement of Claim 26, wherein said array of such reaction chambers                    
              is operatively connected via an array of microinjectors to a microelectrophoresis array.                 
                                                    THE REFERENCES                                                     
                     In rejecting the appealed claims under 35 U.S.C. §102, the Examiner relies on                     
              the following reference:                                                                                 
              Pace (Pace)                       4,908,112                        Mar. 13, 1990                       
                     In rejecting the appealed claims under 35 U.S.C. §103, the Examiner relies upon                   
              the following references:                                                                                
              Heller et al. (Heller)             5,632,957                        May  27, 1997                       
              Northrup et al. (Northrup I)       5,639,423                        Jun. 17, 1997                       
                     In rejecting the appealed claims for obviousness-type double patenting, the                       
              Examiner relies upon the following reference:                                                            
              Northrup et al., (Northrup II)     5,589,136                        Dec. 31, 1996                       
                                                                              (filed Jun. 20, 1995)                    
                                                 THE REJECTIONS                                                        
                     Claims 27-29 and 32 stand rejected under 35 U.S.C. §112, second paragraph, as                     
              being indefinite for failing to particularly point out and distinctly claim the subject matter           
              which the Appellant regards as the invention.                                                            
                     Claims 1, 2, 3, 6, 9, 11, 17, 22, 30, and 33-37 stand rejected under 35 U.S.C.                    
              §102(b) as being anticipated by Pace.                                                                    

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