Ex Parte SIIKA-AHO et al - Page 6




              Appeal No. 2001-0355                                                                                      
              Application No. 08/750,069                                                                                


              satisfy the hexenuronidase activity required by the independent claims on appeal by                       
              reducing the amount of HexAX3 and thereby removing “a part of the hexenuronic acid                        
              groups” (appealed independent claim 1).  For this reason alone, it would be appropriate                   
              to sustain each of the examiner’s § 103 rejections.                                                       
                     The examiner also considers the data of declaration Table 1 to reflect that the                    
              prior art enzymes exhibit hexenuronidase activity by reducing the combined total of the                   
              HexAX3 and HexAX2 quantities (e.g., the combined total of these quantities on the                         
              substrate (i.e., 1140+2310=3450) was reduced after treatment with Pulpzyme HA (i.e.,                      
              0+3210=3210)).  We are aware that the application file record contains a response to                      
              the examiner’s afore noted position which analyzes the declaration and explains that the                  
              reduction in combined total quantities observed by the examiner, in fact, does not                        
              evince hexenuronidase activity.  The proffered analysis and explanation, however, are                     
              not presented by the declarant under § 1.132.  Rather, the analysis and explanation are                   
              presented by the attorney of record in the previously mentioned communication filed                       
              March 24, 2000 as paper no. 19.  For this reason, the analysis and explanation must be                    
              regarded as attorney argument, not evidence.                                                              





                     In sum, the declaration data plainly shows a reduction in total combined                           

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