Ex Parte HOLMES et al - Page 3



              Appeal No. 2001-0636                                                                  Page 3                
              Application No. 08/824,513                                                                                  
              alternating hydrophobic and hydrophilic amino acids, complementary and structurally                         
              compatible1, wherein the peptides are less than 12 amino acids in length.                                   
                     In stating the rejection on pages 3-4 of the Examiner's Answer, the examiner                         
              emphasizes one fact, i.e., the vast majority of the original disclosure of this application                 
              describes the present invention in terms of the amphiphilic peptides being of 12 or more                    
              amino acids in length.  However, that is not to say the original disclosure of this                         
              application fails to describes amphiphilic peptides which have the “alternating,                            
              complementary and structural” requirements but contain fewer than 12 amino acids in                         
              length.  For example, original claim 1 of this application was directed to a method for in                  
              vitro cell culture as is present claim 38, but placed no length restriction on the                          
              amphiphilic peptides which form the macroscopic membranes.                                                  
                     In this regard, we note that the examiner has not rejected the claims on appeal                      
              under the written description requirement  of 35 U.S.C. § 112, first paragraph.  Given                      
              that appellants have described an invention broader than claim 1 of the '343 patent, the                    
              issue becomes whether one skilled in the art would be able to make and use the                              
              claimed invention to the extent it reads upon amphiphilic peptides having the                               
              “alternating, complementary, structural” properties but contain fewer than 12 amino                         
              acids.                                                                                                      







                     1  Hereinafter, these three properties will be referred to as “alternating,                          
              complementary and structural.”                                                                              





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