Appeal No. 2001-0697 Page 4 Application No. 09/125,033 invention applies CO2 as a displacing acid which is surprising as CO2 is about 7 orders of magnitude weaker than sulfuric acid used [in the prior art] and also much weaker than carboxylic acids.”). See also pages 13-14. Discussion The examiner rejected claims 1-21 and 23-27 as obvious in view of the combined teachings of March, either of Walkup I or Walkup II, and Cockrem. She cited March as teaching that “esterification of carboxylic acids with alcohols is well known.” The Walkup patents (which have the same specification) are cited for disclosing a process similar to that of the instant claims, but using ammonia to control the pH of the fermentation medium, rather than a sodium- or calcium-containing base, thus producing ammonium lactate salt in the medium. the examiner cites Cockrem as teaching “production of lactic acid and lactic acid esters from fermentation broths . . . using bases such as ammonia, calcium carbonate, calcium hydroxide or sodium hydroxide.” Examiner’s Answer, page 4. The examiner concluded that [i]t would have been obvious to the ordinary artisan that any salt of any carboxylic acid would be useful in the esterification of said acid with an alcohol. . . . Cockrem et al. teach the specific salts recited by the claimed invention. . . . It would also have been obvious to the ordinary artisan to use a sodium or calcium base in neutralizing the fermentation broth with the production of the sodium or calcium salt of the acid present in said broth and to use said salt(s) in the esterification process as taught by Walkup et al. with the reasonable expectation that the reaction would run to completion with the production of an ester of said acid as taught by the prior art. Examiner’s Answer, pages 4-5.Page: Previous 1 2 3 4 5 6 7 8 9 10 NextLast modified: November 3, 2007