Ex parte EYAL - Page 4



                  Appeal No. 2001-0697                                                             Page 4                     
                  Application No. 09/125,033                                                                                  

                  invention applies CO2 as a displacing acid which is surprising as CO2 is about 7                            
                  orders of magnitude weaker than sulfuric acid used [in the prior art] and also                              
                  much weaker than carboxylic acids.”).  See also pages 13-14.                                                
                                                        Discussion                                                            
                         The examiner rejected claims 1-21 and 23-27 as obvious in view of the                                
                  combined teachings of March, either of Walkup I or Walkup II, and Cockrem.                                  
                  She cited March as teaching that “esterification of carboxylic acids with alcohols                          
                  is well known.”  The Walkup patents (which have the same specification) are                                 
                  cited for disclosing a process similar to that of the instant claims, but using                             
                  ammonia to control the pH of the fermentation medium, rather than a sodium- or                              
                  calcium-containing base, thus producing ammonium lactate salt in the medium.                                
                  the examiner cites Cockrem as teaching “production of lactic acid and lactic acid                           
                  esters from fermentation broths . . . using bases such as ammonia, calcium                                  
                  carbonate, calcium hydroxide or sodium hydroxide.”  Examiner’s Answer, page 4.                              
                  The examiner concluded that                                                                                 
                         [i]t would have been obvious to the ordinary artisan that any salt of                                
                         any carboxylic acid would be useful in the esterification of said acid                               
                         with an alcohol. . . .  Cockrem et al. teach the specific salts recited                              
                         by the claimed invention. . . .  It would also have been obvious to                                  
                         the ordinary artisan to use a sodium or calcium base in neutralizing                                 
                         the fermentation broth with the production of the sodium or calcium                                  
                         salt of the acid present in said broth and to use said salt(s) in the                                
                         esterification process as taught by Walkup et al. with the                                           
                         reasonable expectation that the reaction would run to completion                                     
                         with the production of an ester of said acid as taught by the prior                                  
                         art.                                                                                                 
                  Examiner’s Answer, pages 4-5.                                                                               







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