Appeal No. 2001-1240 Page 4 Application No. 08/374,520 “hydrogen, alkyl, alkenyl, alkynyl, aryl, or heteroaryl, hydroxy, protected hydroxy, or together with R1 forms a carbonate.” In the structures shown in the claims of the ‘726 and ‘449 patents, by contrast, the positions corresponding to R14 and R14a can only be hydrogens. Thus, a baccatin III derivative having an alkyl group at positions R14 and R14a, or a method of making such a derivative, would infringe the instantly pending claims without infringing the claims of the ‘726 and ‘449 patents. This single difference, while not the only difference between the pending and patented claims, is enough in itself to defeat a rejection for “same invention” double patenting. The rejections under 35 U.S.C. § 101 are reversed. 2. The “new matter” rejection The examiner rejected product claims 45-56 under 35 U.S.C. § 112, first paragraph, as “being new matter.” Examiner’s Answer, page 4. He explained that “[t]he scope of the claims 45 to 56 is broader than the scope of the original claims which required additional search and/or consideration.” Id. Later in the Examiner’s Answer, the examiner elaborated on the prosecution history of claims 45-56: Prior to the first Office action, the compound claims are claims 5 to 8, 25 to 28 with a certain scope. After the first Office action, appellants canceled claims 5 to 8, 25 to 28 and replaced them with the instant claims 45 to 56 (on appeal) with a scope broader than the scope of the original claims 5 to 8 and 25 to 28. The new claims embody various species which are not enabled by the specification such as R6 and R6a are not hydrogen; R7, R7a, R9, R9a, R10, R10a are hydrogen; R14 and R14a are not hydroxy. Page 6.Page: Previous 1 2 3 4 5 6 7 8 9 NextLast modified: November 3, 2007