Ex Parte HASELKORN et al - Page 3


                    Appeal No.  2001-1842                                                                        Page 3                      
                    Application No.  08/684,005                                                                                              
                                                                                                                                            

                    thereby.”  Id.  To make up for this deficiency in Bauer, the examiner simply                                             
                    asserts that it is well known in the art to transform and express heterologous                                           
                    genes in a large variety of different host cells.  Answer, pages 4-5.                                                    
                             The claimed invention requires, inter alia, that the gene encoding the                                          
                    sucrose synthase polypeptide be operably linked to a heterologous promoter that                                          
                    expresses the gene.  According to the examiner, when Bauer is combined with                                              
                    the well known knowledge in the art “it would have been obvious to one of                                                
                    ordinary skill in the art to insert the gene of Bauer into an expression vector and                                      
                    to express the gene in order to produce large quantities of sucrose synthase.”                                           
                             Upon review of this record, it is our opinion that the examiner failed to                                       
                    evaluate the question of obviousness using the correct legal standard.  The                                              
                    examiner may establish a case of prima facie obviousness “only by showing                                                
                    some objective teaching in the prior art or that knowledge generally available to                                        
                    one of ordinary skill in the art would lead that individual to combine the relevant                                      
                    teachings of the references.”  In re Fritch, 972 F.2d 1260, 1265, 23 USPQ2d                                              
                    1780, 1783 (Fed. Cir. 1992).  “The factual inquiry whether to combine references                                         
                    must be thorough and searching.”  In re Lee, 277 F.3d 1338, 1345, 61 USPQ2d                                              
                    1430, 1433  (Fed. Cir. 2002), quoting McGinley v. Franklin Sports, Inc., 262 F.3d                                        
                    1339, 1351-52, 60 USPQ2d 1001, 1008 (Fed. Cir. 2001).  Moreover, it is                                                   
                    improper for this board, and for that matter the examiner, to hold claims                                                
                    unpatentable for obviousness based solely on conclusory statements about what                                            
                    is “common knowledge” or “well known” in the art, without objective evidence in                                          







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