Ex Parte MICHELOTTI et al - Page 4



             Appeal No. 2001-1946                                                              Page 4               
             Application No. 08/874,463                                                                             
             examiner refer to any previous Office action for an appropriate explanation of the                     
             rejection.  All we have is a statement identifying the claims under rejection (1-4                     
             and 8-10); the reference relied on (Michelotti); and the relevant statutory provision                  
             (35 U.S.C. § 103(a)).                                                                                  
                    As best we can judge, the explanation supporting the rejection of claims 1-4 and                
             8-10 may be found in the first Office action mailed January 2, 1998 (Paper No. 3, page                 
             3).  There the examiner apparently invokes a per se rule of obviousness, i.e., a per se                
             rule that the S enantiomer recited in applicants' claims would have been prima facie                   
             obvious in view of the racemate disclosure by Michelotti.  According to the examiner,                  
                    racemic N-Acetonylbenzamides are well known for their fungicidal activity                       
                    as taught by Michelotti and the biological activity of compounds is well                        
                    known to be dependent upon the optical isomeric form since biological                           
                    molecules such as proteins, carbohydrates etc. are themselves optical                           
                    enantiomers [Paper No. 3, page 3, emphasis added].                                              
             Therefore, the examiner argues, "it would have been obvious to one skilled in the art to               
             prepare compositions containing either S or R enantiomers of [racemic] N-                              
             Acetonylbenzamides (compounds of Machelotti [sic])" (id.).  As stated in In re Ochiai,                 
             71 F.3d 1565, 1572, 37 USPQ2d 1127, 1133 (Fed. Cir. 1995), however,                                    
                    The use of per se rules, while undoubtedly less laborious than a search                         
                    and comparison of the claimed invention--including all its limitations--with                    
                    the teachings of the prior art, flouts section 103 and the fundamental case                     
                    law applying it.  Per se rules that eliminate the need for a fact-specific                      
                    analysis of claims and prior art may be administratively convenient for                         
                    PTO examiners and the Board.  Indeed, they have been sanctioned by                              
                    the Board as well.  But reliance on per se rules of obviousness is legally                      
                    incorrect and must cease.                                                                       

             Accordingly, to the extent that the examiner would apply a per se rule of obviousness to               
             reach the S enantiomer recited in applicants' claims, in lieu of the comprehensive                     





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