Ex Parte WIER - Page 5



              Appeal No.  2001-2027                                                                    Page 5                 
              Application No. 09/059,573                                                                                      
              an assay which would analyze lymphocytes for lymphocyte activation@ (Examiner=s                                 
              Answer, pages 4-5), when the examiner has not identified a reason to combine the                                
              references in the first place.                                                                                  
                      The fact that the prior art could have been modified in a manner consistent with                        
              appellants= claims would not have made the modification obvious unless the prior art                            
              suggested the desirability of the modification.  In re Gordon, 733 F.2d 900, 902, 221                           
              USPQ 1125, 1127 (Fed. Cir. 1984).  On this record, the only reason or suggestion to                             
              combine the references in the manner claimed comes from appellant=s specification.                              
              Accordingly, we are constrained to reverse the rejection of claims 1, 32, 33, 35 and 36                         
              under 35 U.S.C. ' 103.                                                                                          
              The rejection of claim 34                                                                                       
                      Claim 34 depends from claim 1 and requires a viral, bacterial or fungal inducing                        
              agent.  The examiner=s proposed combination of Ishizaka and Melnicoff forms the basis                           
              of this rejection as well, with the addition of Gottlieb as evidence that it was known in                       
              the art Athat any particular antigen or mitogen may be used to stimulate a[n] [immune]                          
              response.@  The addition of Gottlieb does nothing to cure the underlying deficiency in                          
              the proposed combination of Ishizaka and Melnicoff, thus, the rejection of claim 34                             
              under 35 U.S.C. ' 103 is reversed as well.                                                                      
                                                        REVERSED                                                              

                                                                          )                                                   
                                     Toni R. Scheiner                    )                                                   
                                     Administrative Patent Judge          )                                                   
                                                                          )                                                   
                                                                          ) BOARD OF PATENT                                   
                                                                          )                                                   
                                     Demetra J. Mills                    ) APPEALS AND                                       
                                     Administrative Patent Judge          )                                                   
                                                                          ) )INTERFERENCES                                    
                                                                          )                                                   


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