Ex Parte TRYGGVASON et al - Page 2




          Appeal No. 2001-2413                                                         
          Application No. 09/167,894                                                   


               1.  A perfusion apparatus for the prolonged delivery of gene            
          therapy pharmaceuticals in a perfusate to target tissues                     
          comprising a means for allowing the conduction of perfusate, a               
          reservoir for the perfusate, a means for propelling the                      
          perfusate, a means for oxygenating the perfusate, and suitable               
          means for connecting the apparatus to the target wherein the                 
          reservoir, means for propelling the perfusate, means for                     
          oxygenating the perfusate and target organ are serially connected            
          by a means to allow the conduction of perfusate.                             
               7.  A perfusion system for the delivery of pharmaceuticals              
          in a perfusate to target tissues, said system comprising a                   
          perfusate solution containing gene therapy pharmaceuticals                   
          wherein said perfusate solution is maintained at a temperature of            
          about 37°C, a means for allowing the conduction of perfusate, a              
          reservoir for the perfusate, a means for propelling the                      
          perfusate, a means for oxygenating the perfusate, and suitable               
          means for connecting the apparatus to a target tissue wherein the            
          reservoir, means for propelling the perfusate, means for                     
          oxygenating the perfusate and target tissue are serially                     
          connected by a means to allow the conduction of perfusate.                   

                                    THE PRIOR ART                                      
               The reference relied on by the examiner to support the final            
          rejection is:                                                                
          Sadri                    5,338,662            August 16, 1994                

                                    THE REJECTIONS                                     
               Claim 1 stands rejected under 35 U.S.C. § 102(e) as being               
          anticipated by Sadri.                                                        




          limitations refer to the same structure.                                     
                                          2                                            





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