Ex Parte WINTER et al - Page 8


               Appeal No. 1998-3272                                                                                                   
               Application 08/461,393                                                                                                 

               would have reasonably arrived at metallocene compounds which satisfy each of the limitations of                        
               the claimed metallocene compounds encompassed by claims 23 and 36.  See In re Payne,                                   
               606 F.2d 303, 315, 203 USPQ 245, 254-55 (CCPA 1979) (“An obviousness rejection based on                                
               similarity in chemical structure and function entails the motivation of one skilled in the art to                      
               make a claimed compound, in the expectation that compounds similar in structure will have                              
               similar properties.”); see also In re Jones, 958 F.2d 347, 349-51, 21 USPQ2d 1941, 1943-44                             
               (Fed. Cir. 1992) (“Conspicuously missing from this record is any evidence, other than the PTO’s                        
               speculation (if it be called evidence) that one of ordinary skill in the herbicidal art would have                     
               been motivated to make the modifications of the prior art salts necessary to arrive at the claimed                     
               . . . salt.”); In re Dillon, 919 F.2d 688, 692-93, 16 USPQ2d 1897, 1901 (Fed. Cir. 1990)(in banc)                      
               (“This court . . . reaffirms that structural similarity between claimed and prior art subject matter,                  
               proved by combining references or otherwise, where the prior art gives reason or motivation to                         
               make the claimed compositions, creates a prima facie case of obviousness, and that the burden                          
               (and opportunity) then falls on an applicant to rebut that prima facie case.”); In re Grabiak,                         
               769 F.2d 729, 731-32, 226 USPQ 870, 872 (Fed. Cir. 1985) (“[W]e have concluded that                                    
               generalizations should be avoided insofar as specific chemical structures are alleged to be prima                      
               facie obvious one from the other. . . . [I]n the case before us there must be adequate support in                      
               the prior art for the ester/thioester change in structure, in order to complete the PTO’s prima facie                  
               case and shift the burden of going forward to the applicant.”).                                                        
                       Turning now to the evidence in the Winter (I) and (III) declarations, Winter (I) apparently                    
               provides evidence of unexpected results with respect to the two species of appealed claim 18,                          
               which contain particular “aryl” groups in the R6 position and zirconium dichloride as the central                      
               transition metal atom, as the examiner cites this evidence as the reason for not rejecting this                        
               claim (answer, page 6).  We presume that the examiner has also not rejected appealed claim 17,                         
               drawn to the subgenus of each of the claimed species containing zirconium, in view of such                             
               results.  In the absence of a statement to the contrary in the answer, we further presume that the                     
               examiner also considers the results in Winter (III) to be unexpected because the only position                         
               taken by the examiner for maintaining the ground of rejection even in view of such evidence is                         
               that the same “is not commensurate in scope with the claims” (id.).                                                    


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