Ex Parte LINSLEY et al - Page 17




              Appeal No. 1999-2330                                                                                      
              Application No. 08/219,200                                                                                

              Furthermore, claim language must be analyzed “not in a vacuum, but always in light of                     
              the teachings of the prior art and of the particular application disclosure as it would be                
              interpreted by one possessing the ordinary skill in the pertinent art.”  In re Moore, 439                 
              F.2d 1232, 1235, 169 USPQ 236, 238 (CCPA 1971).                                                           
                     The examiner argues that it is unclear what is meant by “B7" and by the phrase                     
              ?containing amino acid residues from about position 1 to about position 215 of the                        
              amino acid sequence corresponding to the extracellular domain of B7 antigen because                       
              their characteristics are ambiguous and not defined.”  Answer, page 5.  The examiner                      
              suggests that “while the name itself may have some notion of the activity of the protein,                 
              there is nothing in the claims which distinctly claims the protein and variants thereof.                  
              Others in the field may isolate the same protein and give such an entirely different                      
              name.  Also B7 can refer to a number of distinct proteins expressed on various tissues                    
              and in various animal species.”  The examiner continues, “Claiming biochemical                            
              molecules by a particular name given to the protein by various workers in the field fails                 
              to distinctly claim what that protein is and what the compounds are made up of.  This                     
              language is vague and indefinite since it can encompass many different proteins and is                    
              not apparent which particular antigen is being referred to.”   Answer, page 5.                            
                     As discussed herein, we have interpreted the term ?B7" consistent with the                         
              prosecution history and specification pages 6 and 11 as that described in Freeman                         
              1989, which is now referred to in the art as B7-1.   We find no ambiguity in its meaning,                 
              as defined in the specification.                                                                          
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