Ex Parte QUAY - Page 8




          Appeal No. 2000-0827                                                        
          Application 08/466,104                                                      


          least that is required for a description of the invention under             
          the first paragraph of § 112."), the examiner argues that "[a]s             
          in Winkhaus, the pairing of the specific gas with a specific                
          shell material might be seen in hindsight to be possible.                   
          However, there is no indication that these particular                       
          combinations were originally considered to be a part of                     
          Applicant's invention."  Answer at 4.                                       
               In response to the rejection, Appellant relies on two                  
          declarations by a technical expert, Dr. Pamela Hilpert: (a) the             
          July 31, 1998, "Second Declaration of Pamela Hilpert, M.D.,                 
          Ph.D." (hereinafter the "Second Hilpert Declaration"); and                  
          (b) the March 24, 1999, "Third Declaration of Pamela Hilpert,               
          M.D., Ph.D." (hereinafter the "Third Hilpert Declaration").  Both           
          of these declarations discuss "Contrast Agents in Diagnostic                
          Ultrasound," which was authored by Dr. Hilpert and forms                    
          Chapter 3 (hereinafter the "Hilpert Chapter") at pages 30-42 of             
          Volume 1 of Diagnostic Ultrasound (1991).                                   
               Beginning with the matter of how to construe the rejected              
          claims, we do not understand the examiner's above-quoted                    
          assertion that "the instant claims are drawn to a composition               
          wherein each gas is combined with a specific sub-genus of shell             
          material . . . [of] human protein" (Answer at 4)(emphasis added)            

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