Ex Parte WEINER et al - Page 5


                     Appeal No.  2001-2633                                                               Page ~ PAGE ~5~                             
                     Application No.  07/323,182                                                                                                     
                     was made to select a glycolipid from the genus of membrane components                                                           
                     disclosed by Kikuchi.  To the contrary, the examiner simply asserts (Answer,                                                    
                     bridging paragraph, pages 4-5), “[o]ne would have been motivated to select                                                      
                     glycolipids as the membrane component because they are listed as being among                                                    
                     the [genus of] exemplary lipids.”  For the foregoing reasons, it is our opinion that                                            
                     the examiner’s assertion is incompatible with the relevant legal precedent.                                                     
                     Similarly, we are not persuaded by the examiner’s assertion (Answer, page 4),                                                   
                     “[o]ne would have been motivated to use acetaminophen or sodium salicylate                                                      
                     because they are mentioned by name in the patent.”  The examiner failed to                                                      
                     explain why one of ordinary skill in the art would have selected acetaminophen                                                  
                     or sodium salicylate from the genus of drugs disclosed by Kikuchi for inclusion in                                              
                     a liposome consisting essentially of a glycolipid.  Once again, for the reasons set                                             
                     forth above, it is our opinion that the examiner’s assertion is incompatible with                                               
                     the relevant legal precedent.                                                                                                   
                              On reflection, it is our opinion that the examiner failed to meet his burden                                           
                     of providing the evidence necessary to establish a prima facie case of                                                          
                     obviousness.  Accordingly, we reverse the rejection of claims 81, 83-86 and 88-                                                 
                     97 under 35 U.S.C. § 103 as being unpatentable over Kikuchi.                                                                    
                     Kikuchi in view of Lenk:                                                                                                        
                              Relying on Kikuchi as set forth above, the examiner finds (Paper No. 48,                                               
                     page 4), that Kikuchi do not teach a stable plurilamellar liposome as set forth in                                              
                     appellants’ claim 82.  To make up for this deficiency, the examiner relies on                                                   
                     Lenk.  According to the examiner (Answer, page 5), “[o]ne would have been                                                       







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