Ex Parte HOKAMA et al - Page 5


              Appeal No.  2002-0426                                                  Page               5                  
              Application No. 09/115,797                                                                                      
              § 102(b) as anticipated by ‘525 and remand the application to the examiner for                                  
              further consideration.                                                                                          
              The rejection over Park:                                                                                        
                      According to the examiner (Answer, pages 5-6):                                                          
                      Park teaches a kit for the detecting the [sic] presence of ciguatoxin …                                 
                      which comprises supports for binding toxin, a fixer for fixing toxin to the                             
                      support, an assay reagent, and a buffer solution for washing the fixed                                  
                      toxin-bound supports.  The fixation reagent, assay reagent and wash                                     
                      solution inherently are supplied in separate containers. … The LIQUID                                   
                      PAPER-coated end or membrane end of a “test” support is inserted into                                   
                      the incision to contact the fish sample (col. 4[,] lines 3-5).                                          
              According to appellants’ claimed invention, the first container contains a solvent                              
              for extracting toxins from fish tissue and for facilitating toxin binding to the                                
              membrane.  In this regard, the examiner finds (Answer, page 11), “Park teaches                                  
              the use of absolute methanol[2] for fixing.  Park teaches the incorporation of an                               
              organic solvent into the preparation to reduce the amount of oil left on the                                    
              support and aids in drying of the support after impregnation with the okadaic acid                              
              composition.”  The examiner is correct in that Park teaches the use of absolute                                 
              methanol as a fixation reagent.  See Park, column 8, lines 30-31.  The examiner                                 
              is also correct in that Park teaches the use of mixtures of oil in butanol, or oil in                           
              hexane, as a carrier.  However, what the examiner appears to have missed is                                     
              that appellants’ claimed invention comprises a first container, containing a                                    
              solvent for both extracting toxins from fish tissue and for facilitating toxin binding                          
              to the membrane.  It appears that the examiner has misinterpreted the claimed                                   


                                                                                                                             
              2 We note that the ‘525 patent teaches the use of absolute methanol as an extraction reagent.  See ‘525,        
              column 4, lines 40-54, “[t]he solvent is preferably absolute methanol … the fish tissue is immersed in the      
              methanol for a sufficient amount of time to form a fish extract.”                                               




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