Appeal No. 2002-0798 Page 2 Application No. 09/107,688 its chemical or electrochemical properties. The transformed scaffold moiety is then reacted with a further mixture of chemical reactive compounds to provide a library. Claim 13, which is illustrative of the subject matter on appeal, reads as follows: 13. A method for preparing a chemical library comprising: reacting a mixture of at least four chemical reactive compounds with at least one scaffold moiety to provide a mixture of reaction products; transforming said scaffold moiety in said reaction products to alter at least one of its chemical or electrochemical properties and; reacting said transformed scaffold moiety in said products with a further mixture of at least four chemical reactive compounds to provide said library. (Emphasis added). The Prior Art References The prior art references relied on by the examiner are: Rutter et al. (Rutter) 5,010,175 Apr. 23, 1991 Joran 5,364,851 Nov. 15, 1994 Baindur et al. (Baindur) 5,646,285 Jul. 8, 1997 Ostresh et al. (Ostresh), "'Libraries from libraries': Chemical Transformation of Combinatorial Libraries to Extend the Range and Repertoire of Chemical Diversity," Proc. Nat'l Acad. Sci. USA, Vol. 91, pp. 11138-42 (Nov. 1994) The Rejections The appealed claims stand rejected as follows: (1) claims 13, 23, and 26 under 35 U.S.C. § 102(b) as described by Rutter; (2) claims 13 and 23 through 26 under 35 U.S.C. § 103(a) as unpatentable over the combined disclosures of Rutter, Baindur, and Ostresh; (3) claims 13, 23, 26, and 30 under 35 U.S.C. § 103(a) as unpatentable overPage: Previous 1 2 3 4 5 6 7 8 9 10 NextLast modified: November 3, 2007