Appeal No. 2002-0869 Application No. 08/580,384 references Snyder and Howard, submitted with respect to the issue of expectation of success in the copending application to support their position with evidence. In addition, appellants argue in the current record that Esmon does not teach the presence of TNF in the ocular environment, and provides no evidence that the biochemical cascade of events associated with inflammation and TNF occurs in either the aqueous or vitreous humor of the eye. Brief, page 9. Upon return of the application to the examiner, if the examiner determines it appropriate to maintain the obviousness rejection in view of the currently cited references, the examiner should make of record evidence confirming that the biochemical cascade of events associated with inflammation and TNF occurs in the eye. CONCLUSION We vacate the rejections of claims 22-27 under 35 U.S.C. § 103(a) for obviousness over Galin or Iverson in view of Bang and Esmon, and of claims 28-29 under 35 U.S.C. § 103(a) for obviousness over Galin or Iverson in view of Bang and Esmon in further view of Stocker. Upon return of the application, the examiner should take a step back and review the record in copending appeal Serial No. 08/696,698 (Appeal No. 2001-1685) with respect to the issue of expectation of success and other matters consistent with the discussion herein. 5Page: Previous 1 2 3 4 5 6 7 NextLast modified: November 3, 2007