Appeal No. 2002-1409 Application 09/381,444 the claimed invention as a whole, including each and every limitation of the claims, without recourse to the teachings in appellant’s disclosure. See generally, In re Rouffet, 149 F.3d 1350, 1358, 47 USPQ2d 1453, 1458 (Fed. Cir. 1998); Pro-Mold and Tool Co. v. Great Lakes Plastics Inc., 75 F.3d 1568, 1573, 37 USPQ2d 1626, 1629-30 (Fed. Cir. 1996); In re Fine, 837 F.2d 1071, 1074-76, 5 USPQ2d 1596, 1598-1600 (Fed. Cir. 1988); In re Dow Chem. Co., 837 F.2d 469, 473, 5 USPQ2d 1529, 1531-32 (Fed. Cir. 1988). The requirement for objective factual underpinnings for a rejection under § 103(a) extends to the determination of whether the references can be combined. See In re Lee, 277 F.3d 1338, 1343, 61 USPQ2d 1430, 1433-34 (Fed. Cir. 2002), and cases cited therein. On this record, we must agree with appellant (e.g., reply brief, page 11, first full paragraph) that the examiner has not made out a prima facie case of obviousness with respect to the claimed invention. We find that Model would have reasonably suggested to one of ordinary skill in this art3 that “4,2’,4’-trichloro-2-hydroxy-diphenyl ether,” which is specified in the appealed claims as “2,4, 4’-trichloro-2’-hydroxy-diphenyl ether” and is also known commercially as IrgasanŽ DP 300 and Triclosan, can be used to impart antimicrobial properties to molded plastic articles, including those prepared by injection molding (e.g., col. 1, lines 15-36; col. 4, lines 24-35; col. 6, lines 27-39; col. 18, lines 21 and 27; and Examples X through XII; specification, page 3, first full paragraph). Similarly, we find that Dubin would have reasonably suggested to one of ordinary skill in this art that 2,2’-thiobis (4,6-dichlorophenol) and 2,2’methylenebis-(3,4,6-trichloro) phenol, which are specified in the appealed claims as 3,5,3’,5’-tetrachloro-2,2’-dihydroxydiphenyl sulfide and 3,5,6,3’,5’,6’-hexachloro-2,2’- dihydroxydiphenylmethane, respectively, can be used to impart antimicrobial properties to molded articles, including those prepared by extrusion, and indeed, used “for the production of any item on which micro-organisms might be passed or where they come in contact with the surface of the plastic material” (e.g., col. 1, lines 18-30 and 46-69; col. 2, lines 17-23; col. 2, line 2 Answer, pages 3-5. 3 It is well settled that a reference stands for all of the specific teachings thereof as well as the inferences one of ordinary skill in this art would have reasonably been expected to draw therefrom, see generally, In re Fritch, 972 F.2d 1260, 1264-65, 23 USPQ2d 1780, 1782-83 (Fed. - 2 -Page: Previous 1 2 3 4 5 NextLast modified: November 3, 2007