Appeal No. 2002-1630 Page 19 Application No. 09/175,713 aminooxypentane-modified chemokine would be the same as the polynucleotide encoding the unmodified chemokine. On return of this application, the examiner should consider whether claim 1 is sufficiently definite to meet the requirements of 35 U.S.C. § 112, second paragraph. In addition, if a polynucleotide encoding an aminooxypentane- modified chemokine is, in fact, the same as a polynucleotide encoding an unmodified chemokine, the examiner should consider whether any of the claims are anticipated by prior art disclosing a chemokine-encoding polynucleotide. Summary We reverse the rejection for inadequate written description because the examiner has not adequately explained why those skilled in the art would not have recognized the specification’s description as showing that Appellants were in possession of the invention now claimed. We also reverse the rejection of claims 6-9 for nonenablement, because the examiner has not explained why undue experimentation would have been required to make and use fragments of the recited amino-terminal-modified chemokines, or variants encoded by polynucleotides that hybridize under stringent conditions. However, we affirm the rejection of claims 1-5, 10-14, 17, and 18 for nonenablement, because claim 5 reads on amino-terminal-modified chemokines that vary from the recited chemokines in any way and to any degree, and the specification does not provide sufficient guidance to practice the very broad scope of this claim. Claims 1-4, 10-14, 17, and 18 fall with claim 5.Page: Previous 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 NextLast modified: November 3, 2007