Ex Parte WEINBERG et al - Page 1



                       The opinion in support of the decision being entered today was not written   
                             for publication and is not binding precedent of the Board.             

                                                                            Paper No. 68            

                     UNITED STATES PATENT AND TRADEMARK OFFICE                                      
                                           __________                                               

                         BEFORE THE BOARD OF PATENT APPEALS                                         
                                     AND INTERFERENCES                                              
                                            __________                                              
                           Ex parte ROBERT WEINBERG, CLIFFORD TABIN                                 
                                       and SCOTT BRADLEY                                            
                                           ___________                                              
                                       Appeal No. 2003-0054                                         
                                      Application No. 08/308,193                                    
                                            __________                                              
                                       HEARD: April 15, 2003                                        
                                            __________                                              
           Before WILLIAM F. SMITH, LORIN and SCHEINER, Administrative Patent Judges.               
           SCHEINER, Administrative Patent Judge.                                                   
                                       DECISION ON APPEAL                                           
                 This is a decision on appeal under 35 U.S.C. § 134 from the final rejection of     
           claims 93, 99 and 100.  Claims 95 and 97, the only other claims pending at the time of   
           the final rejection, have been canceled by an amendment under 37 CFR § 1.116 filed       
           with appellant’s Brief (paper no. 62).  Claims 93, 99 and 100 read as follows:           
                 93.  A nucleic acid probe capable of detecting a single base difference between    
           a nucleotide sequence present in a previously isolated oncogene and a nucleotide         
           sequence present in a corresponding previously isolated proto-oncogene, wherein the      
           single base difference is responsible for conversion of the proto-oncogene to the        
           oncogene and the single base difference is located in a sequence recognized by a         
           restriction enzyme.                                                                      
                 99.  The probe of claim 93, wherein the oncogene is a human ras oncogene.          
                 100.  The probe of claim 93, wherein the human ras oncogene differs from the       
           human ras proto-oncogene in the codon for position 12.                                   
                 Claims 93, 99 and 100 stand rejected under the doctrine of obviousness-type        



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