Ex Parte ANDERSON et al - Page 2




                Appeal No. 2003-0569                                                                            Page 2                  
                Application No. 09/381,044                                                                                              

                                                         INTRODUCTION                                                                   
                        Claim 11 is illustrative of the subject matter on appeal:                                                       
                        11. A pharmaceutical composition which can be administered orally, allowing the                                 
                controlled release of at least one active substance, comprising:                                                        
                        a) the said at least one active substance,                                                                      
                        b) between 5 and 60% by weight, relative to the total weight of the composition, of at                          
                least one excipient, selected from the group consisting of inert matrices, hydrophilic matrices,                        
                lipid matrices, mixtures of inert matrices and of lipid matrices, and mixtures of hydrophilic                           
                matrices and of inert matrices, with the exception of mixtures comprising a polyacrylic acid and                        
                at least one hydrophilic matrix of the cellulose type; and                                                              
                        c) between 5 and 50% by weight, relative to the total weight of the composition, of at                          
                least one alkalinizing agent soluble in an aqueous phase under physiological pH conditions,                             
                selected from the group consisting of alkali or alkaline-earth metal hydroxides, carbonates,                            
                bicarbonates, phosphates, sodium borate and basic salts of organic acids.                                               
                        Claims 11-20 stand rejected under 35 U.S.C. § 103(a).  As evidence of obviousness, the                          
                Examiner relies upon the following prior art references:                                                                
                Kwan et al. (Kwan) (PCT)               WO 94/09761                     May 11, 1994                                     
                Norling et al. (Norling) (PCT)         WO 95/34291                     Dec. 21, 1995                                    
                        The Examiner rejects all the claims as obvious over Norling alone or Norling in view of                         
                Kwan.                                                                                                                   
                        We reverse for the following reasons.                                                                           













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