Ex Parte Angello - Page 5


                 Appeal No. 2003-0736                                                           Page 5                    
                 Application No. 09/720,007                                                                               

                 references would have suggested to one of ordinary skill in the art.”  In re Young,                      
                 927 F.2d 588, 591, 18 USPQ2d 1089, 1091 (Fed. Cir. 1991).                                                
                         “Obviousness does not require absolute predictability of success.”  In re                        
                 O’Farrell, 853 F.2d 894, 903, 7 USPQ2d 1673, 1681 (Fed. Cir. 1988).  However,                            
                 the prior art must provide a basis for a reasonable expectation of success.  See,                        
                 e.g., In re Dow Chemical Co., 837 F.2d 469, 473, 5 USPQ2d 1529, 1531 (Fed.                               
                 Cir. 1988) (“[T]he expectation of success must be founded in the prior art, not in                       
                 the applicant’s disclosure.”).                                                                           
                         In this case, we agree with Appellant that the examiner’s references do                          
                 not support a prima facie case of obviousness.  First, as noted by Appellant,                            
                 none of the examiner’s references even mentions renal colic, and therefore the                           
                 references would not have suggested the specific, claimed method.  See In re                             
                 Ochiai, 71 F.3d 1565, 1569, 37 USPQ2d 1127, 1131 (Fed. Cir. 1995) (“The test                             
                 of obviousness vel non is statutory.  It requires that one compare the claim’s                           
                 ‘subject matter as a whole’ with the prior art ‘to which said subject matter                             
                 pertains.’”); In re Wilder, 429 F.2d 447, 450, 166 USPQ 545, 548 (CCPA 1970)                             
                 (“[E]very limitation positively recited in a claim must be given effect in order to                      
                 determine what subject matter that claim defines.”).  Since the cited references                         
                 do not even mention renal colic, we cannot agree with the examiner that the                              
                 references would have suggested a method of treating renal colic.                                        
                         The examiner asserted that “[i]t is general knowledge that typical                               
                 treatment of renal colic consists of the administration of morphine as a pain                            
                 killer,” Examiner’s Answer, page 3, although he did not cite any evidence in the                         





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