Ex Parte Albers et al - Page 5


                 Appeal No. 2003-0839                                                          Page 5                    
                 Application No. 09/646,339                                                                              

                 those skilled in the art could have made products with the recited property “by                         
                 routine experimentation,” she has pointed to no evidence that those skilled in the                      
                 art would have been motivated to do so.  See In re Fritch, 972 F.2d 1260, 1266,                         
                 23 USPQ2d 1780, 1783 (Fed. Cir. 1992):  “The mere fact that the prior art may                           
                 be modified in the manner suggested by the Examiner does not make the                                   
                 modification obvious unless the prior art suggested the desirability of the                             
                 modification.”                                                                                          
                        The examiner argued that those skilled in the art would have been led to                         
                 modify the surface roughness of the prior art products “to determine a suitable                         
                 surface roughness to control the rate of release.”  Examiner’s Answer, page 4.                          
                 Thus, she argued, “one would determine a suitable surface roughness in order to                         
                 obtain the desired effect of controlled release.”  Id.  “[T]he discovery of an                          
                 optimum value of a variable in a known process is normally obvious,” but one of                         
                 the exceptions to that rule is where the parameter optimized was not recognized                         
                 in the prior art as one which would affect the results.  See In re Antonie, 559 F.2d                    
                 618,620, 195 USPQ 6, 8 (CCPA 1977).  Here, the examiner has cited no                                    
                 evidence to show that those skilled in the art would have recognized a                                  
                 relationship between surface roughness and rate of release.                                             
                        “Even when obviousness is based on a single prior art reference, there                           
                 must be a showing of a suggestion or motivation to modify the teachings of that                         
                 reference.”  In re Kotzab, 217 F.3d 1365, 1370, 55 USPQ2d 1313, 1316 (Fed.                              
                 Cir. 2000).  Modifying “prior art references without evidence of such a                                 
                 suggestion, teaching, or motivation simply takes the inventor’s disclosure as a                         





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