Appeal No. 2003-0914 3
Application No. 09/192,713
wherein:
R3 is selected from CF3, COOH, (C1-C6)alkylCOOH, (C1-C6) alkyl and (C1-
C6)alkylCF3;
n is selected from 0, 1 or 2;
R4 is selected from (C1-C3)alkyl or (C0-C3)alkylphenyl wherein said phenyl
moiety is substituted with 0, 1, 2, 3, 4 or 5 J moieties where J at each occurrence
is selected from halogen, (C1-C4)alkyl, NO2, CN, perfluoro(C1-C3)alkyl, OH, CF3,
(C2-C4)alkenyl, (C2-C4)alkynyl, or O-(C1-C4)alkyl;
R5 is phenyl wherein the phenyl group is substituted with 0, 1, 2, 3, 4 or 5 J
moieties where J is as in the definition of R4;
R6 is selected from hydrogen and (C1-C3) alkyl;
R7 is selected from hydrogen and C(O)(C1-C3)alkyl, and
with the proviso that said compound is not 7-chloro-4-hydroxy-2-[1-(N-
phenylcarbamoyl)ethyl]-1,2,5,10-tetrahydropyridazino[4,5-b]quinoline-1,10-
dione, 7-chloro-4-hydroxy-2-cyclohexyl-1,2,5,10-tetrahydropyridazino[4,5-
b]quinoline-1,10-dione, 7-chloro-4-hydroxy-2-(1-methylbenzyl)-1,2,5,10-
tetrahydropyridazino[4,5-b]quinoline-1,10-dione, 7-chloro-4-hydroxy-2-(1-
methylbutyl)-1,2,5,10-tetrahydropyridazino[4,5-b]quinoline-1,10-dione, 7-chloro-
4-hydroxy-2-(1-methyl-2-phenylethyl)-1,2,5,10-tetrahydropyridazino[4,5-
b]quinoline-1,10-dione, or 7-chloro-4-hydroxy-2-(1,3-dimethylbutyl)-1,2,5,10-
tetrahydropyridazino[4,5-b]quinoline-1,10-dione.
THE REFERENCE OF RECORD
As evidence in support of the obviousness type double patenting rejection, the
examiner relies upon the following reference:
Bare et al. (Bare) 5,837,705 Nov. 17, 1998
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