Appeal No. 2003-1012 Page 3 Application No. 09/340,111 also include a buffer system, such as acetic or citric acids, and sweeteners such as sucrose, glucose or saccharin. See Examiner’s Answer, page 3. The rejection goes on to note that the reference “does not teach specifically that the sweetener acts as the anti-irritant in the composition,” but asserts that the reference teaches that “the removal of calculus deposits will treat inflammation.” Id. at 3-4. The rejection also asserts that while the Ebetino reference does not teach the specific amount of sweetener present in the anticalculus composition, it would only require minimal experimentation to determine those levels, and “[t]he results must be those that accrue from the specific limitations.” Id. at 4. The rejection concludes: The reference teaches acetic and citric acids, along with their salts as possible buffering systems. It is well known in the art that a buffering solution comprises a weak acid and the salt of that weak acid, and that buffering solutions have a maximum and minimum pH. Attached is an excerpt from Method in Enzymology, which discloses the pH ranges for both acetic and citric buffer solutions. The acetic buffer allows a range from 3.6 to 5.6, and the citric buffer allows a range from 3.0 to 6.2. Therefore, as the reference teaches that these buffers can be employed in their composition, and these buffers are known to cause acidic pH levels, the limitation to an acidic solution is disclosed. One of ordinary skill in the art would have been motivated to use the composition disclosed by [Ebetino], containing sweeteners, in order to treat inflammation caused by calculus on teeth. One of ordinary skill in the art would have expected the inflammation to lessen due to the removal or loosening of the calculus. Therefore, the invention as a whole would have [been] [sic] prima facie obvious to one of ordinary skill in the art at the time the invention was made. Id. at 4.Page: Previous 1 2 3 4 5 6 NextLast modified: November 3, 2007