Ex Parte PORTMANN et al - Page 3



              Appeal No. 2003-1199                                                                  Page 3                 
              Application No. 09/125,329                                                                                   
















                                                    The References                                                         
                     The prior art references relied on by the examiner are:                                               
              Meier (Meier '680)                  4,789,680                    Dec. 6, 1988                                
              Meier (Meier '262)                  199,262                      Oct. 29, 1986                               
              (European Patent Application)                                                                                
              Muenzel (Muenzel (1966)), "Design and Effect of Pharmaceuticals," Progress in Drug                           
              Research, Vol. 10, pp. 227-30 (1966)                                                                         
              Muenzel (Muenzel (1970)), "Design and Effect of Pharmaceuticals," Progress in Drug                           
              Research, Vol. 14, pp. 309-21 (1970)                                                                         


                                                     The Rejections                                                        
                     The previously entered rejections under 35 U.S.C. § 102 and 35 U.S.C. § 112                           
              have been withdrawn (Paper No. 16, section (10)).                                                            
                     Claims 1 through 9, 13, 14, 16 through 21, 26, 28, 30, and 31 stand rejected                          
              under 35 U.S.C. § 103(a) as unpatentable over the combined disclosures of Meier '680,                        
              Meier '262, Muenzel (1966), and Muenzel (1970).  Those same claims also stand                                





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