Ex Parte TULLY et al - Page 4


                  Appeal No. 2003-0835                                                           Page 4                    
                  Application No. 09/419,371                                                                               

                                                     DISCUSSION                                                            
                  1.     Rejection under 35 U.S.C. § 112, second paragraph                                                 
                         Claims 9-20 and 39-50 stand rejected under 35 U.S.C. § 112, second                                
                  paragraph.                                                                                               
                         According to the rejection, “the metes and bounds of ‘dcreb2, activators,                         
                  repressors, CREB/CREM/ATF-1 subfamily members, activator isoforms and                                    
                  repressor isoforms’ remain indefinite as the metes and bounds of the terms                               
                  cannot be readily discerned by the skilled artisan as claimed.”  Examiner’s                              
                  Answer, page 4.                                                                                          
                         “The test for definiteness is whether one skilled in the art would                                
                  understand the bounds of the claim when read in light of the specification.”  Miles                      
                  Laboratories, Inc. v. Shandon, Inc., 997 F.2d 870, 875, 27 USPQ2d 1123, 1126                             
                  (Fed. Cir. 1993).  Claims are in compliance with 35 U.S.C. § 112, second                                 
                  paragraph, if “the claims, read in light of the specification, reasonably apprise                        
                  those skilled in the art and are as precise as the subject matter permits.”                              
                  Hybritech, Inc. v. Monoclonal Antibodies, Inc., 802 F.2d 1367, 1385, 231 USPQ                            
                  81, 94-95 (Fed. Cir. 1987).                                                                              
                         Appellants argue, and we agree, that the terms dcreb2, activators,                                
                  repressors, CREB/CREM/ATF-1 subfamily members, activator isoforms and                                    
                  repressor isoforms, are definite when read in light of the specification.  See                           
                  Appeal Brief, page 7.  The examiner argues that “neither the metes nor the                               
                  bounds of the claims are clear or established without reading the specification                          
                  into the claims.”  The test for definiteness is, however, is whether one skilled in                      





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