Ex Parte GOLDBERG et al - Page 10


                 Appeal No.  2003-0837                                              Page ~ PAGE ~10~                     
                 Application No.  09/078,531                                                                             
                                                       Claim 38                                                          
                        According to the examiner (Answer, page 7), “[c]laim 38 recites the further                      
                 administration of inhibitors of IL-1.”  While not expressly stated by the examiner,                     
                 Grande does not teach this subject matter.  To make up for this deficiency in                           
                 Grande, the examiner relies on Bruder and Pettipher.  Answer, pages 7-8.                                
                        Bruder and Pettipher, however, fail to make up for the deficiency in                             
                 Grande.  See supra.  Accordingly, we reverse the rejection of claim 38 under 35                         
                 U.S.C. § 103 as being unpatentable over Grande in view of Bruder and Pettipher.                         
                                                       Claim 39                                                          
                        According to the examiner (Answer, page 7), “[c]laim 39 recites the further                      
                 administration of inhibitors of osteochondral precursor cells.”  While not expressly                    
                 stated by the examiner, Grande does not teach this subject matter.  To make up                          
                 for this deficiency in Grande, the examiner relies on Nevo and Itay.  Answer,                           
                 pages 7-8.                                                                                              
                        Nevo and Itay, however, fail to make up for the deficiency in Grande.  See                       
                 supra.  Accordingly, we reverse the rejection of claim 39 under 35 U.S.C. § 103                         
                 as being unpatentable over Grande in view of Nevo and Itay.                                             

















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