Ex Parte Hill et al - Page 9



            Appeal No. 2003-1019                                                          Page 9              
            Application No. 09/524,132                                                                        
                   Appellants’ point is well taken.  We have no doubt that the prior art could be             
            modified in a manner consistent with appellants’ specification and claims.  The fact that         
            the prior art could be so modified, however, would not have made the modification                 
            obvious unless the prior art suggested the desirability of the modification.  In re Gordon,       
            733 F.2d 900, 902, 221 USPQ 1125, 1127 (Fed. Cir. 1984).  Here, we find no reason                 
            stemming from the prior art relied on by the examiner which would have led a person               
            having ordinary skill in the art to modify Townsend’s HPLC protocol to meet the specific          
            limitations of the claims directed to analysis of conjugated estrogens.                           
                   In our view, the references cited by the examiner do not support a prima facie             
            case of obviousness.  Accordingly, the rejection of claims 1-5 , 8-22 and 25-48 under 35          
            U.S.C. § 103 is reversed.                                                                         


























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