Appeal No. 2003-1738 Page 2
Application No. 08/739,396
(b) attaching said species of bioorganic molecule onto
said attachment surface; and
(c) subdividing said unit of substantially planar material to
form a plurality of separate tiles, a surface of each of said
separate tiles comprising a portion of said attachment
surface;
and
2) affixing separate tiles from the said batches of tiles in
predetermined spatial positions on a support.
The examiner relies on the following reference:
Rava et al. (Rava) 5,545,531 Aug. 13, 1996
Claims 4, 5, 8-11, 37-53, 58, and 59 stand rejected under 35 U.S.C.
§ 102(e) as anticipated by Rava.
Claims 4, 5, 8-11, and 37-61 stand rejected under 35 U.S.C. § 103 as
obvious in view of Rava.
We reverse both rejections.
Background
“Arrays of immobilized probes are currently being developed for use in
assays to detect and identify components in biological samples and for screening
molecular libraries. The ability to screen for multiple species of molecules in a
single assay test is particularly valuable for purposes of drug discovery and
clinical genetics. . . . [In] prior art methods, the probe molecules are synthesized
in situ on a solid support surface at predetermined locations.” Specification,
page 1.
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