Appeal No. 2003-1792 Application No. 09/434,598 We do not find that appellant’s claim grouping conforms with Rule 1.192. While appellants have grouped claims 34 and 35 separately from claim 37 (Brief, page 4), they have not presented separate argument as to why claims 34 and 35 are patentable in view of the cited art. Since the individual claims of each group are not argued, we decide this appeal with respect to the prior art rejections on the basis of claim 37, as representative of Group I, and claim 36, as representative of Group II. Thus, claims 34 and 35 fall with claim 37. 37 CFR §1.192(c)(7) (2002). DISCUSSION Background The claimed invention is directed to a set of affector oligomers for specifically reducing the expression of an RNA molecule of interest. Affector RNA molecules include ribozymes, external guide sequences, anti-sense RNA and triple helix forming RNA that inhibit expression of target RNA molecules. Specification, page 1. Disclosed in the specification is a method of identifying affector molecules by screening or selecting for those RNA molecules that alter the expression of a fusion transcript which includes the sequence of an RNA molecule of interest, from a library of potential affector RNA molecules. Specification, page 8. Inhibition of expression of the fusion transcript prevents expression of the reporter protein. This allows inhibition of expression to be monitored by detecting expression of the reporter protein. Id. The inhibition of expression is accomplished by interaction of a nucleic acid molecule involved in the expression of the RNA molecule of interest with an affector molecule. 3Page: Previous 1 2 3 4 5 6 7 8 9 10 11 12 NextLast modified: November 3, 2007