Appeal No. 2004-0245 Application 09/265,926 position, including hydrogenolysis of the 6-chloropurine intermediate as the last step to obtain the final product. Accordingly, one of ordinary skill in this art routinely following the teachings of Grinter would have arrived at the claimed compound encompassed by appealed claim 5 without resort to appellant’s specification and claims. See generally, Merck & Co., Inc. v. Biocraft Labs., Inc., 874 F.2d 804, 807, 10 USPQ2d 1843, 1845-46 (Fed. Cir. 1989); In re Lemin, 332 F.2d 839, 841, 141 USPQ 814, 815-16 (CCPA 1964). Therefore, since a prima facie case of obviousness has been established by the examiner over Grinter, we have again evaluated all of the evidence of obviousness and nonobviousness based on the record as a whole, giving due consideration to the weight of appellant’s arguments in the brief. See generally, Johnson, supra; Piasecki, supra; Rinehart, supra. We are not persuaded by appellant’s sole argument with respect to this ground of rejection (brief, page 6) that the “examples” of Grinter require removal of the chloro group in scheme “(i).” Indeed, as the examiner argues with respect to the examples of the reference (see above p. 7), all of the teachings of the reference must be considered. See generally, Merck v. Biocraft, 874 F.2d at 807, 10 USPQ2d at 1846 (quoting Lamberti, supra) (“But in a section 103 inquiry, ‘the fact that a specific [embodiment] is taught to be preferred is not controlling, since all disclosures of the prior art, including unpreferred embodiments, must be considered.’”). Accordingly, based on our consideration of the totality of the record before us, we have weighed the evidence of obviousness found in Grinter with appellants’ countervailing evidence of and argument for nonobviousness and conclude that the claimed invention encompassed by appealed claim 5 would have been obvious as a matter of law under 35 U.S.C. § 103(a). The examiner’s decision is affirmed. No time period for taking any subsequent action in connection with this appeal may be extended under 37 CFR § 1.136(a). AFFIRMED - 13 -Page: Previous 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 NextLast modified: November 3, 2007