Appeal No. 2004-0290 Application No. 09/742,692 (page 12 of principal brief, second paragraph, emphasis added). Appellants repeat in their reply brief the argument that “Beggs does not appear to disclose the same antibody part, or other stain-binding parts as those utilized in the present invention” (page 2, second paragraph, emphasis added). Manifestly, this speculation on the part of appellants falls far short of establishing the requisite clear line of demarcation between enzymes within the scope of claim 1 and those fairly disclosed by Beggs. As for appellants’ argument that Beggs does not suggest any dependency or relationship between the pI value of the stain- binding part of the enzyme and the pH of the wash solution, it is not necessary for the reference to disclose such a property of the enzyme that is inherently possessed. Also, the question arises, based on the close correspondence between appellants’ and Beggs disclosure, how one of ordinary skill in the art would be enabled to select enzymes having the claimed pI without resorting to undue experimentation. Totally lacking in appellants’ principal and reply briefs is any argument that an actual specific enzyme, or class of enzymes, is not within the Beggs disclosure. -6–Page: Previous 1 2 3 4 5 6 7 8 NextLast modified: November 3, 2007