Appeal No. 2004-0291 Application No. 09/091,561 Moreover, even if we assume for the sake of argument that the examiner had established a prima facie case of lack of enablement, we do not find the examiner has sufficiently addressed the Declaration argument and evidence made of record by appellants in support of enablement which would appear to reasonably support appellants position that the experimentation required to isolate the claimed antibodies was routine and used methodologies well known in the art. After evidence or arguments are submitted by the appellant in response to rejection based on lack of enablement, patentability is determined on the totality of the record, by a preponderance of evidence with due consideration to persuasiveness of the argument. On balance, we believe that the totality of the evidence presented by the examiner and appellant weighs in favor of finding the claimed invention is enabled by the present specification. The rejection of claims for lack of enablement is reversed. CONCLUSION The rejection of claims 25-30 and 32-35 under 35 U.S.C. 112, first paragraph for lack of enablement is reversed. 8Page: Previous 1 2 3 4 5 6 7 8 9 10 NextLast modified: November 3, 2007