Appeal No. 2004-0450 Page 5 Application No. 09/785,936 phosphatase enzyme; or 3) the formation of an aqueous slurry or mixture of vegetable protein material and an acid phosphatase enzyme or an enzyme preparation containing an acid phosphatase enzyme, where the acid phosphatase enzyme or enzyme preparation is present in the slurry or mixture in an amount of from about 0.1% to about 10% by weight of protein material (dry). [Appeal Brief, page 6] RNA Degradation The ‘343 patent does not explicitly mention RNA or the degradation of RNA. Nonetheless, applicants acknowledge that Commercially available protein concentrates and isolates . . . contain some impurities which are undesirable in products such as infant formulas. Specific impurities which are undesirable in vegetable protein isolates and concentrates include phytic acid, phytates, ribonucleic acids, ash, and minerals bound to phytic acid, phytates, or ribonucleic acids which are unavailable for human assimilation such as phosphorus, calcium, chloride, iron, zinc, and copper. It is desirable to provide methods for reducing the levels of these impurities in vegetable protein isolates and concentrates, particularly for use in products such as infant formulas. [Specification, page 1, lines 12 through 19] According to applicants, “[p]hytase enzyme compositions are not recognized to reduce the levels of ribonucleic acid materials and associated minerals in vegetable protein materials since the most common phytases . . . do not degrade the ribonucleic acid structure.” (Id., page 2, lines 26 through 29). Applicants have attached several publications to their Appeal Brief and Reply Brief as support for this argument. For example, according to applicants, the Leach publication (Appendix C of the Brief) teaches that “one skilled in the art would not expect phosphatases to degrade polymeric nucleotides such as ribonucleic acids” (Appeal Brief, page 13, first full paragraph). Also, the Cech patent (Appendix D of thePage: Previous 1 2 3 4 5 6 7 8 9 10 11 12 13 NextLast modified: November 3, 2007