Appeal No. 2004-1259 Application No. 09/832,355 therein. Moreover, the examiner indicates in the rejection under 35 U.S.C.§ 102 that “Angiopoietin is known in the art to reduce [vessel] permeability”, meeting the limitations of claim 17. Answer, page 13. We do not find the examiner has established a prima facie case of lack of enablement supported by sufficient argument or evidence. As we have found that the examiner has not established a prima facie case of lack of enablement in the first instance, we do not reach appellants’ evidence in support of enablement. The rejection of claim 17 for lack of enablement is reversed. From the above, it would appear that the specification reasonably describes products having the claimed properties. The rejection of claim 17 for lack of written description is reversed. 35 U.S.C. §102(a) Claims 1-4, 9, 16-19, 32-34, 39-40 and 43-45 stand rejected under 35 U.S.C. § 102(a), as anticipated by Davis. The examiner argues that (Answer, page 13): Davis [ ] disclose fusion proteins comprising the receptor binding domains of two ligands, which ligands may be the same or different, as well as multimers thereof. Preferred embodiments include Angiopoietin-1 and -2, and EPH family ligands, see claims. At page 9 a species comprising VEGF and angiopoietin is specifically described, as is the definition that 'receptor binding domain” is “the minimal portion of the ligand that is necessary to bind it's receptor.” 22Page: Previous 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 NextLast modified: November 3, 2007