Ex Parte Safinya et al - Page 4


                  Appeal No.  2004-2078                                                           Page 4                    
                  Application No. 09/754,509                                                                                
                  disclosure of the invention itself.   Diversitech Corp. v. Century Steps, Inc.,  850                      
                  F.2d 675, 678-79,  7 USPQ2d 1315, 1318 (Fed. Cir. 1988); In re Geiger, 815                                
                  F.2d 686, 688, 2 USPQ2d 1276, 1278 (Fed. Cir. 1987);  Interconnect Planning                               
                  Corp. v. Feil, 774 F.2d 1132, 1143,  227 USPQ 543, 551 (Fed. Cir. 1985).  On                              
                  the record before us, we find no reasonable suggestion for combining the                                  
                  teachings of the references relied upon by the examiner in a manner which would                           
                  have reasonably led one of ordinary skill in this art to arrive at the claimed                            
                  invention.  The initial burden of presenting a prima facie case of obviousness                            
                  rests on the examiner.  In re Oetiker, 977 F.2d 1443, 1445, 24 USPQ2d 1443,                               
                  1444  (Fed. Cir. 1992).  In our opinion, the examiner failed to provide the                               
                  evidence necessary to support a prima facie case of obviousness.                                          
                         Accordingly, we reverse the rejection of claims 1, 3, 4, 6-17 and 23-27                            
                  under 35 U.S.C. § 103(a) over the combination of Ghyczy and Woodle.                                       


                  The combination of Ghyczy, Woodle and Kanno:                                                              
                         According to the examiner (Answer, page 5), “Kanno shows that it is                                
                  common practice in the art to encapsulate … [bacteriorhodopsin] in                                        
                  liposomes….”  While Kanno addresses an additional feature of the claimed                                  
                  invention as set forth in claim 5, Kanno fails to make up for the deficiency in the                       
                  combination of Ghyczy and Woodle discussed above.                                                         












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