Interference 103,781
SENIOR PARTY PATENT
Named Inventors: Michael J. Adang, Thomas A. Rocheleau,
Donald J. Merlo, and Elizabeth E. Murray
Application: Application 08/057,191, filed May 3,
1993, now U.S. Patent 5,380,831, issued
January 10, 1995
Title: Synthetic Insecticidal Crystal Protein
Gene
Assignee: Mycogen Plant Science, Inc. (Paper
No. 13)
Accorded benefit
for the purpose of
priority of: Applications 07/827,844, filed
January 28, 1992, now abandoned,
and Application 07/242,482, filed
September 9, 1988, now abandoned
Count 1
A method of designing a synthetic Bacillus
thuringiensis gene to be more highly expressed in plants,
comprising the steps of:
a) analyzing the coding sequence of a gene derived
from Bacillus thuringiensis which encodes an insecticidal
protein toxin, and modifying a portion of said coding
sequence to yield a modified sequence which contains a
greater number of codons preferred by the intended plant
host than did said coding sequence, or
b) analyzing the coding sequence of a gene derived
from Bacillus thuringiensis which encodes an insecticidal
protein toxin, and modifying a portion of said coding
sequence to yield a modified sequence which contains a
greater number of codons preferred by the intended plant
host than did said coding sequence and fewer plant
polyadenylation signals than said coding sequence.
The claims of the parties which were designated to
correspond to this count were:
-10-
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