Appeal No. 2004-2079 Page 3
Application No. 09/754,958
-COOR7, -CONH2, -CONR8R9, -CONH(CH2)nOH, -CH2OH, -CH2NH2,
-N=C=O, -N=C=S, -SO3H, -SO2NH(CH2)nNH , -CONH(CH2)nNH2
wherein and [sic] the -NH2 group could also be substituted by (C1-C4)
alkyl or a commonly used amino protecting group;
n is 2-8;
with the proviso that only one of R1-R6 is nitro;
R7 is a commonly used carboxyl protecting or carboxyl activating
group;
R8 or R9 is hydrogen and the other is lower alkyl (C1-C4), phenyl,
benzyl, or R8 and R9 are part of a 5 or 6 membered ring;
R10 and R11 are independently hydrogen or (C1-C4)alkyl; and
R12 is (C1-C10)alkyl, [or] phenyl, which both can be substituted by (C1-
C4) alkyl, protected amino group or halogen; and
D and D' are independently a bond or a spacer selected from α,ω-
diamino-alkanes, diaminocyclohexyl, bis-(aminomethyl)-substituted
phenyl, α-amino-ω-hydroxy-alkanes, alkylamines, cyclic alkylamines
or cyclic alkyldiamines or amino acids without or with additional
functionality in the side chain.
No prior art is relied upon by the examiner.
GROUNDS OF REJECTION
Claims 17, 18, 20 and 21 stand rejected under 35 U.S.C. § 112, first
paragraph, as being based on a specification that fails to adequately describe the
claimed invention.
Claims 17, 18, 20 and 21 stand rejected under 35 U.S.C. § 112, first
paragraph, as being based on an insufficient disclosure to enable the scope of
the claimed invention.
Claims 17-21 stand rejected under 35 U.S.C. § 112, second paragraph as
indefinite.
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